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1

NEW TRENDS IN NUCLEOSIDE BIOTECHNOLOGY

MIKHAILOPULO I.A.,MIROSHNIKOV A.I.

Journal:

Acta Naturae (англоязычная версия)

Year:

2010

Language:

english

File:

PDF, 6.14 MB

english, 2010

2

Synthesis of anhydro psicofuranosyl nucleosides

Jarkko Roivainen, Jouko Vepsäläinen, Alex Azhayev, Igor A. Mikhailopulo

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 74 KB

english, 2002

3

Effect of dephosphorylated 2′,5′-trioligoadenylate on the entry of sodium ions into human neuroblastoma cells

O. M. Rozhmanova, E. V. Dolgaya, N. Kh. Pogorelaya, I. S. Magura, Z. Yu. Tkachouk, I. A. Mikhailopulo

Journal:

Neurophysiology

Year:

2008

Language:

english

File:

PDF, 338 KB

english, 2008

4

The High-Anti Conformation of 7-Halogenated 8-Aza-7-deaza-2′-deoxy-guanosines: A Study of the Influence of Modified Bases on the Sugar Structure of Nucleosides

Frank Seela, Georg Becher, Helmut Rosemeyer, Hans Reuter, Guido Kastner, Igor A. Mikhailopulo

Journal:

Helvetica Chimica Acta

Year:

1999

Language:

english

File:

PDF, 303 KB

english, 1999

5

Nucleotides

Evgeny I. Kvasyuk, Igor A. Mikhailopulo, Joseph W. Homan, Kathryn T. Iacono, Nicholas F. Muto, Robert J. Suhadolnik, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1999

Language:

english

File:

PDF, 157 KB

english, 1999

6

A Novel Route for the Synthesis of Deoxy Fluoro Sugars and Nucleosides

Igor A. Mikhailopulo, Grigorii G. Sivets

Journal:

Helvetica Chimica Acta

Year:

1999

Language:

english

File:

PDF, 139 KB

english, 1999

7

Chemo-Enzymatic Synthesis of 3-Deoxy-β-D-ribofuranosyl Purines

Vladimir N. Barai, Anatoli I. Zinchenko, Ludmilla A. Eroshevskaya, Elena V. Zhernosek, Erik De Clercq, Igor A. Mikhailopulo

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 93 KB

english, 2002

8

A Universal Biocatalyst for the Preparation of Base- and Sugar-Modified Nucleosides via an Enzymatic Transglycosylation

Vladimir N. Barai, Anatoli I. Zinchenko, Ludmilla A. Eroshevskaya, Elena N. Kalinichenko, Tamara I. Kulak, Igor A. Mikhailopulo

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 87 KB

english, 2002

9

Mass spectrometry of some modified nucleosides of the pyrimidine and purine series

I. A. Mikhailopulo, E. N. Kalinichenko, G. V. Zaitseva, A. A. Akhrem

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1982

Language:

english

File:

PDF, 646 KB

english, 1982

10

ChemInform Abstract: Nucleotides. Part 52. Synthesis and Biological Activity of New Base- Modified (2′-5′)Oligoadenylate Trimers.

E. I. KVASYUK, T. I. KULAK, O. V. TKACHENKO, S. L. SENTYUREVA, I. A. MIKHAILOPULO, R. J. SUHADOLNIK, E. E. HENDERSON, S. E. HORVATH, M.-X. GUAN, W. PFLEIDERER

Journal:

Year:

1997

File:

PDF, 26 KB

1997

11

ChemInform Abstract: Nucleotides. Part 56. Synthesis and Biological Activity of Modified (2′—5′)Triadenylates Containing 2′-Terminal 2′,3′-Dideoxy-3′-fluoroadenosine Derivatives.

E. I. KVASYUK, T. I. KULAK, O. V. TKACHENKO, S. L. SENTYUREVA, I. A. MIKHAILOPULO, R. J. SUHADOLNIK, E. E. HENDERSON, S. E. HORVATH, M.-X. GUAN, W. PFLEIDERER

Journal:

Year:

1998

File:

PDF, 28 KB

1998

12

ChemInform Abstract: A Novel Route for the Synthesis of Fluorodeoxy Sugars and Nucleosides

Igor A. Mikhailopulo, Grigorii G. Sivets, Natalia B. Khripach

Journal:

Year:

1999

File:

PDF, 24 KB

1999

13

ChemInform Abstract: Nucleotides. Part. 58. Synthesis and Biological Activity of (2′→5′) Oligoadenylate Trimers Containing a 5′-Terminal 5′-Amino-5′-deoxy- or 5′-Amino-3′,5′-dideoxyadenosine Derivative.

Evgeny I. Kvasyuk, Igor A. Mikhailopulo, Joseph W. Homan, Kathryn T. Iacono, Nicholas F. Muto, Robert J. Suhadolnik, Wolfgang Pfleiderer

Journal:

Year:

1999

File:

PDF, 32 KB

1999

14

ChemInform Abstract: Dimeric Oligonucleotide Synthons Containing 2-Deoxy-3-O-phosphonomethyl-α-D-erythro-pentofuranosyl Nucleosides

Igor A. Mikhailopulo, Tamara I. Kulak, Olga V. Tkachenko, Svetlana L. Sentyureva, Frank Seela

Journal:

Year:

1999

File:

PDF, 27 KB

1999

15

ChemInform Abstract: Phosphonate Isostere of Nucleoside 3′- and 2′-Phosphates as Precursors of the Related Oligonucleotides

Igor A. Mikhailopulo, Tamara M. Tsvetkova, Grigorii G. Sivets, Nicolai E. Poopeiko

Journal:

Year:

1999

File:

PDF, 24 KB

1999

16

ChemInform Abstract: Synthesis and Biological Activity of 2′,5′-Oligoadenylate Trimers Containing 5′-Terminal 5′-Amino-5′-deoxy- and 5′-Amino-3′,5′-dideoxyadenosine Derivatives

Evgeny I. Kvasyuk, Igor A. Mikhailopulo, Robert J. Suhadolnik, Earl E. Henderson, Nicholas F. Muto, Kathryn T. Iacono, Joseph Homon, Wolfgang Pfleiderer

Journal:

Year:

1999

File:

PDF, 27 KB

1999

17

ChemInform Abstract: A Novel Route for the Synthesis of Deoxy Fluoro Sugars and Nucleosides.

Igor A. Mikhailopulo, Grigorii G. Sivets

Journal:

Year:

2000

Language:

english

File:

PDF, 36 KB

english, 2000

18

ChemInform Abstract: Pyrophosphoryl Derivatives of 1-(2-Deoxy-3-O-phosphonomethyl-β- and -α-D-erythro-pentofuranosyl)thymine: Synthesis and Substrate Properties Towards Some DNA Polymerases.

Igor A. Mikhailopulo, Tamara I. Kulak, Olga V. Tkachenko, Svetlana L. Sentyureva, Lyubov S. Victorova, Helmut Rosemeyer, Frank Seela

Journal:

Year:

2002

Language:

english

File:

PDF, 35 KB

english, 2002

19

3-Bromopyrazolo[3,4-d]pyrimidine 2′-Deoxy-2′-fluoro-β-D-arabinonucleosides: Modified DNA Constituents with an Unusually Rigid Sugar N-Conformation.

Junlin He, Igor Mikhailopulo, Frank Seela

Journal:

Year:

2003

File:

PDF, 56 KB

2003

20

Enzymatic Synthesis of Nucleoside-5′-O-(1-thiophosphates) and (SP)-Adenosine-5′-O-(1-thiotriphosphate).

Vladimir N. Barai, Anatoli I. Zinchenko, Sergei V. Kvach, Olga I. Titovich, Elena B. Rubinova, Elena N. Kalinichenko, Igor A. Mikhailopulo

Journal:

Year:

2003

File:

PDF, 86 KB

2003

21

Chemo-Enzymatic Synthesis of 3-Deoxy-β-D-ribofuranosyl Purines and Study of Their Biological Properties

Vladimir N. Barai, Anatoli I. Zinchenko, Ludmilla A. Eroshevskaya, Elena V. Zhernosek, Jan Balzarini, Erik De Clercq, Igor A. Mikhailopulo

Journal:

Year:

2004

File:

PDF, 57 KB

2004

22

Ability of Adenosine-2′(3′)-deoxy-3′(2′)-triphosphates and Related Analogues to Replace ATP as Phosphate Donor for all Human and Drosphila melanogaster Deoxyribonucleoside Kinases

Krzysztof Krawiec, Borys Kierdaszuk, Elena N. Kalinichenko, Elena B. Rubinova, Igor A. Mikhailopulo, Staffan Eriksson, Birgitte Munch-Petersen, David Shugar

Journal:

Year:

2004

File:

PDF, 61 KB

2004

23

ChemInform Abstract: Synthesis and Antiviral Activity of Purine 2′,3′-Dideoxy-2′,3′-difluoro-D-arabinofuranosyl Nucleosides.

Grigorii G. Sivets, Elena N. Kalinichenko, Igor A. Mikhailopulo, Mervi A. Detorio, Tami R. McBrayer, Tony Whitaker, Raymond F. Schinazi

Journal:

Year:

2010

File:

PDF, 14 KB

2010

24

ChemInform Abstract: Biologically Important Nucleosides: Modern Trends in Biotechnology and Application

Igor A. Mikhailopulo, Anatoly I. Miroshnikov

Journal:

Year:

2011

File:

PDF, 18 KB

2011

25

Nucleotides. Part XLV. Synthesis of new (2′–5′)adenylate trimers, containing 5′-amino-5′-deoxyadenosine residues at the 5′-end of the oligoadenylate chain, and of its analogues, carrying a 9-[(2-hydroxyethoxy)methyl]adenine residue at the 2′-terminus

Evgeny I. Kvasyuk, Tamara I. Kulak, Igor A. Mikhailopulo, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1995

Language:

english

File:

PDF, 607 KB

english, 1995

26

Nucleotides. Part LII. Synthesis and biological activity of new base-modified (2′–5′)oligoadenylate trimers

Evgeny I. Kvasyuk, Tamara I. Kulak, Olga V. Tkachenko, Svetlana L. Sentyureva, Igor A. Mikhailopulo, Robert J. Suhadolnik, Susan E. Horvath, Earl E. Henderson, Ming-Xu Guan, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1997

Language:

english

File:

PDF, 572 KB

english, 1997

27

Nucleotides. Part LVI. Synthesis and biological activity of modified (2′–5′)triadenylates containing 2′-terminal 2′,3′-dideoxy-3′-fluoroadenosine derivatives

Evgeny I. Kvasyuk, Tamara I. Kulak, Olga V. Tkachenko, Svetlana L. Sentyureva, Igor A. Mikhailopulo, Robert J. Suhadolnik, Earl E. Henderson, Susan E. Horvath, Ming-Xu Guan, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1998

Language:

english

File:

PDF, 446 KB

english, 1998

28

Enzymatic Synthesis of Nucleoside-5′-O-(1-thiophosphates) and (SP)-Adenosine-5′-O-(1-thiotriphosphate)

Vladimir N. Barai, Anatoli I. Zinchenko, Sergei V. Kvach, Olga I. Titovich, Elena B. Rubinova, Elena N. Kalinichenko, Igor A. Mikhailopulo

Journal:

Helvetica Chimica Acta

Year:

2003

Language:

english

File:

PDF, 92 KB

english, 2003

29

Synthesis and Conformational Analysis of 1′- and 3′-Substituted 2-Deoxy-2-fluoro-D-ribofuranosyl Nucleosides

Grigorii G. Sivets, Elena N. Kalinichenko, Igor A. Mikhailopulo

Journal:

Helvetica Chimica Acta

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

30

Synthesis of 2′-Azido-2′,3′-didehydro-2′,3′-dideoxythymidine

Igor A. Mikhailopulo, Galina V. Zaitseva, Elena V. Vaaks, Jan Balzarini, Eric De Clercq, Helmut Rosemeyer, Frank Seela

Journal:

European Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 598 KB

english, 1993

31

13C nuclear magnetic resonance spectroscopy of selected adenine nucleosides: Structural correlation and conformation about the glycosidic bond

A. A. Akhrem, I. A. Mikhailopulo, A. F. Abramov

Journal:

Magnetic Resonance in Chemistry

Year:

1979

Language:

english

File:

PDF, 690 KB

english, 1979

32

Oxidation-reduction sequence for the synthesis of peracylated fluorodeoxy pentofuranosides

Igor A. Mikhailopulo, Grigorii G. Sivets, Nicolai E. Poopeiko, Natalia B. Khripach

Journal:

Carbohydrate Research

Year:

1995

Language:

english

File:

PDF, 1.04 MB

english, 1995

33

Synthesis of a modified 2′, 5′-Adenylate trimer with a 2′,3′-Di-O-(2-Carboxyethyl)-ethylidene terminal group

Evgeny I. Kvasyuk, Tamara I. Kulak, Galina T. Zaitseva, Igor A. Mikhailopulo, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Tetrahedron Letters

Year:

1984

Language:

english

File:

PDF, 198 KB

english, 1984

34

3-Deazaadenosine analogues of p5′A2′p5′A2′p5′A: synthesis, stereochemistry, and the roles of adenine ring nitrogen-3 in the interaction with RNase L

Elena N Kalinichenko, Tatiana L Podkopaeva, Elena V Budko, Frank Seela, Beihua Dong, Robert Silverman, Jouko Vepsäläinen, Paul F Torrence, Igor A Mikhailopulo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 409 KB

english, 2004

35

Synthesis of a new 125I-labeled tyrosine methyl ester conjugate of adenylyl-(2′-5′)-adenylyl-(2′-5′)-[2′,3′-di-O-(2-carboxyethyl)ethylidene]adenosine

Evgeny I. Kvasyuk, Tamara I. Kulak, Svetlana M. Shulyakovskaya, Mikhail V. Makarenko, Igor A. Mikhailopulo, Charubala Ramamurthy, Wolfgang Pfleiderer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 217 KB

english, 1996

36

Ribokinase from E. coli: Expression, purification, and substrate specificity

Dmitry V. Chuvikovsky, Roman S. Esipov, Yuri S. Skoblov, Larisa A. Chupova, Tatyana I. Muravyova, Anatoly I. Miroshnikov, Seppo Lapinjoki, Igor A. Mikhailopulo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 185 KB

english, 2006

37

Biologically important nucleosides: modern trends in biotechnology and application

Igor A. Mikhailopulo, Anatoly I. Miroshnikov

Journal:

Mendeleev Communications

Year:

2011

Language:

english

File:

PDF, 770 KB

english, 2011

38

A food grade approach for the isolation of major alkylresorcinols (ARs) from rye bran applying tailored supercritical carbon dioxide (scCO2) extraction combined with HPLC

Estera Szwajcer Dey, Konstantin Mikhailopulo

Journal:

The Journal of Supercritical Fluids

Year:

2009

Language:

english

File:

PDF, 732 KB

english, 2009

39

Transformation of nucleosides containing β-D-xylofuranuronic acid into the D-ribo analogues

Afanassi A. Akhrem, Anna G. Lapko, Igor A. Mikhailopulo, Victor A. Timoshchuk

Journal:

Carbohydrate Research

Year:

1977

Language:

english

File:

PDF, 110 KB

english, 1977

40

A novel route to terminal chlorodeoxy sugars

A.A. Akhrem, G.V. Zaitseva, I.A. Mikhailopulo

Journal:

Carbohydrate Research

Year:

1973

Language:

english

File:

PDF, 140 KB

english, 1973

41

An unusual transformation of 3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-erythro-hex-3-enofuranose under the action of iodine and thallous salts

Afanassi A. Akhrem, Natalia B. Khripach, Igor A. Mikhailopulo

Journal:

Carbohydrate Research

Year:

1976

Language:

english

File:

PDF, 191 KB

english, 1976

42

Synthesis of uracil nucleosides of D-xyluronic acid derivatives

Afanassi A. Akhrem, Victor A. Timoshchuk, Igor A. Mikhailopulo

Journal:

Carbohydrate Research

Year:

1975

Language:

english

File:

PDF, 345 KB

english, 1975

43

Synthesis and antiviral activity of 3′-C-branched-3′-deoxy analogues of adenosine

Igor A. Mikhailopulo, Nicolai E. Poopeiko, Tamara M. Tsvetkova, Anatoli P. Marochkin, Jan Balzarini, Erik De Clercq

Journal:

Carbohydrate Research

Year:

1996

Language:

english

File:

PDF, 834 KB

english, 1996

44

Low-temperature acetoacetylation of weakly nucleophilic compounds

S.I. Zavialov, V.I. Gunar, I.A. Mikhailopulo, L.F. Ovechkina

Journal:

Year:

1966

Language:

english

File:

PDF, 274 KB

english, 1966

45

A new reaction of acetylsalicyloyl chloride with 1,2-, 1,3- and 1,4-diols and alcohols.

A.A. Akhrem, V.V. Zharkov, G.V. Zaitseva, I.A. Mikhailopulo

Journal:

Tetrahedron Letters

Year:

1973

Language:

english

File:

PDF, 233 KB

english, 1973

46

An unusual reaction of 3-methoxycarbonyl-Δ-pyrazoline with lead tetraacetate

A.A. Akrem, E.I. Kvasyuk, I.A. Mikhailopulo

Journal:

Tetrahedron Letters

Year:

1973

Language:

english

File:

PDF, 218 KB

english, 1973

47

Role of the stereochemistry of 3′-fluoro-3′-deoxy analogues of 2-5A in binding to and activation of mouse RNase L

Elena N. Kalinichenko, Tatjana L. Podkopaeva, Nicolai E. Poopeiko, Merike Kelve, Mart Saarma, Igor A. Mikhailopulo, Jacquelien E. van den Boogaart, Cornelis Altona

Journal:

Recueil des Travaux Chimiques des Pays-Bas

Year:

1995

Language:

english

File:

PDF, 932 KB

english, 1995

48

Enzymatic synthesis of ATP from RNA and adenine

V. N. Barai, A. I. Zinchenko, L. M. Zalashko, L. A. Eroshevskaya, I. A. Mikhailopulo

Journal:

Biotechnology Letters

Year:

1995

Language:

english

File:

PDF, 229 KB

english, 1995

49

A chemo-enzymatic hydrolysis of calcium salt of RNA to nucleosides

V. N. Barai, A. I. Zinchenko, I. A. Bravsevich, I. A. Mikhailopulo

Journal:

Biotechnology Techniques

Year:

1996

Language:

english

File:

PDF, 320 KB

english, 1996

50

Synthesis of 9-(β-d-arabinofuranosyl)guanine using whole cells ofEscherichia coli

A. I. Zinchenko, V. N. Barai, S. B. Bokut, E. I. Kvasyuk, I. A. Mikhailopulo

Journal:

Applied Microbiology and Biotechnology

Year:

1990

Language:

english

File:

PDF, 308 KB

english, 1990

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